Chemohormonal therapy and endocrine function in breast cancer patients
نویسندگان
چکیده
منابع مشابه
Effects of adjuvant chemohormonal therapy on the ovarian and adrenal function of breast cancer patients.
Ovarian and adrenal function were studied in premenopausal breast cancer patients before and at intervals during adjuvant therapy with cyclophosphamide, methotrexate, and 5-fluorouracil (CMF), CMF plus prednisone (CMFP), or CMFP plus tamoxifen (CMFPT). Amenorrhea developed within 10 months of starting therapy in 13 of 15 patients given CMF, 8 of 10 receiving CMFP, and all of 13 CMFPT-treated pa...
متن کاملEffects of Adjuvant Chemohormonal Therapy on the Ovarian and Adrenal Function of Breast Cancer Patients1
Ovarian and adrenal function were studied in premenopausal breast cancer patients before and at intervals during adjuvant therapy with cyclophosphamide, methotrexate, and 5-fluorouracil (CMF), CMF plus prednisone (CMFP), or CMFP plus tamoxifen (CMFPT). Amenorrhea developed within 10 months of starting therapy in 13 of 15 patients given CMF, 8 of 10 receiving CMFP, and all of 13 CMFPT-treated pa...
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In an admirably concise fashion, Dr.Pritchard summarizes the results of trials randomizing tens of thousands of women in order to evaluate various types and uses of endocrine treatment over more than 50 years. I would never have predicted these results when I began my medical career in the early 1970s, or even as late as 1984 when the first overviews of breast cancer therapy were performed by R...
متن کاملEndocrine therapy for breast cancer.
In addition to ovarian ablation by means of surgery or irradiation, a wide variety of endocrine agents are now available for the management of breast cancer, in both the metastatic and adjuvant settings. Currently available endocrine agents include antiestrogens, progestational drugs, and aromatase inhibitors. Randomized trials and meta-analyses have greatly clarified the specific roles of the ...
متن کاملEndocrine Therapy for Breast Cancer
Endocrine therapy is the oldest form of treatment for metastatic breast cancer. The availability of numerous new endocrine agents during the past 10 years has led to significant changes in the use of this form of therapy. This article identifies appropriate candidates for endocrine therapy and describes various treatment options for different subsets of patients with metastatic disease. Overall...
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ژورنال
عنوان ژورنال: Cancer
سال: 1985
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19850701)56:1<63::aid-cncr2820560111>3.0.co;2-7